Have an idea!!!!!!!!
I will make an virus-simulator. You are a virus that wants to dominate the world. As a player you affect the mutations and perhaps infect some people to seed the virus. It will be played on a world map. There are different parameters for each place such as population, infection rate, immunity, wealth, … In the end it's just a complex cellular automata. It will be difficult for me to balance the parameters and make the game fun, but i think this idea is worth a try.