Completely new to pygame but giving pyweek a shot.  Started off by working through a tutorial:

http://qq.readthedocs.org/en/latest/index.html

Dropped about an hour and a half on it and feel like I'm starting to get a little bit of Pygame.  Still no real idea for the game itself.  Potentially some kind of science themed RPG.

Well I started off knowing nothing about pygame and didn't produce anything worth showing.  I know a great deal more now after having worth through several tutorials.  I think that the next challenge I can get a game in.